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为了解随机HLA 配型的供受者配合率的多寡,为器官移植的广泛开展提供一些基础性资料,对336 例肾移植供受者随机的HLAA、B 和DR 抗原配型做了分析。HLA6 个抗原完全错配率为24 .40 % (82/336) ,5 个抗原错配率为33 .33 % (112/336) ,4 个抗原错配率为27 .68 % (93/336) ,3 个抗原错配率为11 .91 % (40/336) ,2 个抗原错配率为2 .68 % (9/336) ,1 个抗原错配率和0 个抗原错配率为0 。随机HLAA、B 和DR1 个抗原配合的在HLAA 抗原为49 .7 % (167/336) ,B 抗原为27 .7 % (93/336) ,DR 抗原为31 .8 % (107/336) 。2 个抗原配合的在A 抗原为4 .76 % (16/336) ,B 抗原为2 .08 % (7/336) ,DR 抗原为3 .27 % (11/336) 。提示:完全配合的HLA 抗原和5 个HLA 抗原配合的几率极低。在随机肾移植供受者中,HLA 抗原A、B 和DR 抗原位点的2 个等位基因完全配合的几率很低。
To understand the random HLA matching with the amount of donor-recipient ratio for the extensive development of organ transplantation to provide some basic information on 336 cases of renal transplant recipients random HLA HLA, B and DR antigen matching do Analysis. HLA-6 antigen complete mismatch rate of 24. 40% (82/336), 5 antigen mismatch rate of 33. 33% (112/336), 4 antigen mismatch rate of 27. 68% (93/336), three antigen mismatch rate of 11. 91% (40/336), two antigens mismatch rate of 2. 68% (9/336), 1 antigen mismatch rate and 0 antigen mismatch rate of 0. Random HLA A, B and DR1 antigen with HLA A antigen 49. 7% (167/336), B antigen 27. 7% (93/336), DR antigen was 31. 8% (107/336). The two antigens in the A antigen is 4. 76% (16/336), B antigen 2. 08% (7/336), DR antigen 3. 27% (11/336). Hint: The odds of fully cooperating HLA antigens and 5 HLA antigens are extremely low. In randomized kidney transplant recipients, HLA alleles A, B and DR antigenic loci two allele with a very low probability of complete cooperation.