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NMDA-Ca2+-NO路径是指存在于神经元内或神经元间由谷氨酸或N-甲基-D-天冬氨酸激活NMDA受体始发的胞内Ca2+增高、生成增加等一系列生理或病理变化途径,该路径存在于中枢神经系统,维持神经元的正常兴奋性,参与海马长时程增强的产生、维持及突触可塑性。在某些神经性疾病中起一定作用
The NMDA-Ca2 + -NO pathway refers to a series of increases in intracellular Ca2 + originating from NMDA receptors activated by glutamate or N-methyl-D-aspartate in neurons or between neurons Physiological or pathological changes in the pathways exist in the central nervous system to maintain the normal excitability of neurons involved in the hippocampal long-term potentiation of production, maintenance and synaptic plasticity. In some neurological diseases play a role