支气管哮喘(简称哮喘)是气道以嗜酸性粒细胞及肥大细胞浸润为主的慢性炎症性病变。以气道广泛的可变性阻塞及气道高反应性为特征。临床表现为反复发作的胸闷、咳嗽、喘鸣、症状可自行或经支气管扩张剂治疗后缓解。难治性哮喘是指经用常规的抗哮喘治疗,其喘息发作仍未 Bronchial asthma (asthma) is a chronic inflammatory disease characterized by eosinophils and mast cell infiltration in the airways. A wide range of airway obstruction and airway hyperresponsiveness characterized. Clinical manifestations of recurrent chest tightness, cough, wheezing, symptoms may be relieved by themselves or by bronchodilator treatment. Refractory asthma refers to the asthmatic attack that has not been treated with conventional anti-asthma treatment