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目的观察依达拉奉(必存)与甲钴胺(弥可保)联合治疗糖尿病周同神经病变(DPN)的疗效。方法将128例患者随机分为治疗组(66例)和对照组(62例),均以糖尿病教育,控制饮食,胰岛素严格控制血糖稳定基础上,治疗组给予依达拉奉与甲钴胺,对照组给予丹参与甲钴胺治疗,连用2周。结果治疗组DPN症状体征,神经传导速度改善明显高于对照组。结论依达拉奉与甲钴胺联用可明显改善DPN的治疗效果。
Objective To observe the efficacy of edaravone (essential) and mecobalamin (methycobalamin) in the treatment of diabetic peripheral neuropathy (DPN). Methods 128 patients were randomly divided into treatment group (66 cases) and control group (62 cases). All of them were on the basis of diabetes education, diet control and strict control of blood glucose and insulin. The treatment group was given edaravone and mecobalamin, Control group was given Salvia and methylcobalamin treatment, once every 2 weeks. Results The symptoms, signs and nerve conduction velocity of DPN in treatment group were significantly higher than those in control group. Conclusion Edaravone and mecobalamin can significantly improve the therapeutic effect of DPN.