Various shaped mafic microgranular enclaves (MMEs) together with several mafic massifs are developed within the Yuegelu granitoid pluton in the eastern part of the Eastern Kunlun. On the basis of detailed field geological surveying and of the results of the petrological and geochemical studies it is suggested that there must be some genetic relationship among the granodiorite host, the MMEs and the hornblende (Hb)-gabbro massifs. Magmatic zircon grains are extracted from samples of granodiorite host rock, Hb-gabbro and the MMEs for U-Pb dating. The U-Pb ages are determined by using SHRIMP Ⅱ technique, which yields the ages of 242±6 Ma, 239±6 Ma and 241±5 Ma, respectively. The overall correspondence in the U-Pb dating results of them excludes the possibility that the MMEs in the granitoids are solid refractory relics from the source region or that they are xenoliths from the wall rocks. It can also rule out the possibility of a later emplacement of basic magma after the solidification of the granitoids. This dating result indicates that they are the products of magma mixing in early-mid Triassic epoch. Among them the granitoid host is chemically akin to the acidic end member during the magma mixing process, the Hb-gabbro is akin to the basic ones while the MMEs are the incompletely mixed basic magma clots trapped in the acidic magma. Combined with the results from other researches on this pluton it is reasonable to consider that in the mid-Triassic the Eastern Kunlun granitoid belt had undergone a process of magma mixing between the mantle-derived basic magma and the crustal acidic magma which indicates that the injection of mantle materials and energy into the crust and the reactions between them played an important role in the formation of the granitoid rocks.