生物膜上嵌有多种酶蛋白，它执行细胞的生物转运、生物转化、能量转换和信息传递等多种功能，保持细胞内环境的平衡，以维持细胞的正常功能。外来化合物所引起的生物膜结合酶活性的改变、可直接影响相应的细胞生理活动，继而对机体造成一定的损害作用。所以，研究外来化合物对生物膜结合酶是否有影响，具有特殊的毒理学意义。木文拟就国内外生物膜结合酶的研究在毒理学中的应用情况作一扼要介绍。 Biomembrane embedded in a variety of enzyme protein, which performs biological transport of cells, biological transformation, energy conversion and information transfer and other functions, to maintain the balance of the intracellular environment in order to maintain the normal function of cells. Foreign compounds caused by changes in the biofilm-binding enzyme activity, can directly affect the corresponding cell physiology activities, and then cause some damage to the body. Therefore, the study of foreign compounds on the biofilm-binding enzyme has an impact, with special toxicological significance. Mu Wen intended to study the application of biofilm binding enzymes in toxicology at home and abroad to make a brief introduction.