咪唑安定可增强氯胺酮的麻醉效果、降低其副作用，多与氯胺酮配伍使用。但咪唑安定是否影响了氯胺酮在学龄前儿童体内的代谢，国内外未见报道。本研究探讨咪唑安定对氯胺酮药代动力学的影响，旨在为临床合理用药提供科学依据。资料和方方法临床资料　选择ＡＳＡⅠ～Ⅱ级择期手 Midazolam can enhance ketamine anesthesia, reduce its side effects, and more compatibility with ketamine. However, whether midazolam affects the metabolism of ketamine in preschool children has not been reported at home and abroad. This study investigated the impact of midazolam on ketamine pharmacokinetics, designed to provide a scientific basis for the rational use of drugs. Materials and methods of clinical data selection ASA Ⅰ ~ Ⅱ elective hand