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目的:比较输尿管癌根治性切除术与输尿管部分切除术治疗早期输尿管尿路上皮癌的临床疗效。方法:我院2005年1月~2014年6月收治早期输尿管尿路上皮癌(Ta~T2a期)患者79例,根据手术方式将79例分为输尿管癌根治性切除组50例和输尿管部分切除术组29例,比较两组患者术后膀胱无复发生存率、输尿管无复发生存率、无远处转移生存率和肿瘤特异性生存率,研究两组手术方式的临床疗效。结果:两组患者术后膀胱无复发生存率(P=0.718)、输尿管无复发生存率(P=0.818)、无远处转移生存率(P=0.533)和肿瘤特异性生存率(P=0.827)比较,差异均无统计学意义。低级别和高级别输尿管肿瘤患者膀胱无复发生存率、输尿管无复发生存率和肿瘤特异性生存率比较,差异均无统计学意义。结论:早期输尿管尿路上皮癌患者行输尿管癌根治性切除术与输尿管部分切除术疗效相似,输尿管部分切除术对于早期输尿管尿路上皮癌患者是一种可行、有效的手术方案。
Objective: To compare the curative effect of radical ureteropectomy and partial ureteropexy in the treatment of early ureteral urothelial carcinoma. Methods: From January 2005 to June 2014, 79 patients with early ureteral carcinoma (Ta ~ T2a) were treated in our hospital. According to the surgical method, 79 patients were divided into 50 cases undergoing radical resection of ureteral carcinoma and partial ureteral resection The patients in operation group were compared in 29 cases. The recurrence-free survival rate, recurrence-free ureter rate, distant metastasis-free survival rate and tumor-specific survival rate were compared between the two groups. The clinical curative effect of the two groups was compared. Results The recurrence-free survival (P = 0.718), ureteral recurrence-free survival (P = 0.818), distant metastasis-free survival (P = 0.533) and tumor-specific survival ), The difference was not statistically significant. Bladder recurrence-free survival, ureteral recurrence-free survival and tumor-specific survival were not significantly different between patients with low-grade and high-grade ureteral tumors. Conclusions: Radical resection of ureteral carcinoma in patients with early urothelial carcinoma is similar to partial resection of ureter. Partial ureterrectomy is a feasible and effective surgical solution for patients with early ureteral urothelial carcinoma.