论文部分内容阅读
目的探讨注射小剂量肉毒毒素 A治疗贲门失弛缓症的方法与疗效。方法内镜下将小剂量肉毒毒素 A分点注射在 10例贲门失弛缓症患者的贲门处。结果 10例患者贲门口明显松弛和扩张。治疗前后贲门口直径分别为 (1.5± 1.11) mm和 (4 .3± 1.42 ) mm(P<0 .0 1) ;治疗前后食管 5分钟存留钡柱高度分别为 (2 2 9.8± 40 .9) mm和 (163 .9± 40 .3 ) mm(P<0 .0 1)。治疗前后经 Eckardt评分分级 ,治疗后均下降 1～ 3个级差。结论内镜下注射小剂量肉毒毒素 A治疗贲门失弛缓症 ,方法简便 ,近期疗效显著
Objective To investigate the method and effect of injecting low dose botulinum toxin A in the treatment of achalasia. Methods A small dose of botulinum toxin A was injected endocardially into the cardia of 10 patients with achalasia. Results 10 patients with cardia obvious relaxation and expansion. Before and after treatment, the diameter of the cardia was (1.5 ± 1.11) mm and (4.3 ± 1.42) mm (P <0.01), respectively. The height of the barium column in the esophagus after 5 minutes of treatment was (2 2 9.8 ± 40.9) ) mm and (163.9 ± 40.3) mm (P <0.01). Before and after treatment by Eckardt grading, after treatment decreased by 1 to 3 levels. Conclusion Endoscopic injection of low-dose botulinum toxin A in the treatment of achalasia is simple and convenient, with a significant short-term effect