作者为阐明抽动秽语综合症(Tourette’s Syndrome TS)临床病程的演变,对1984～1991年间经美国Rochester医疗中心确诊的TS儿童患者进行了回顾性评估。该组均符合TS:DSM—Ⅲ—R诊断标准,具有慢性运动及发声抽动特点,病程一年以上且除外了其他疾病。接受标准神经病学检查和正规神经精神科测试评估。以初期临床评估与近期临床追踪的评估进行比较。其中包括终需接受抗抽搐、抗行为紊乱药物治疗者,近期追踪时病人被分为“控制组”、“改善组”。 To clarify the evolution of the clinical course of Tourette’s Syndrome TS, we retrospectively reviewed TS children diagnosed at the Rochester Medical Center between 1984 and 1991 in the United States. The group were in line with TS: DSM-Ⅲ-R diagnostic criteria, with chronic movement and vocal tics, duration of more than one year and except for other diseases. Subject to standard neurological examination and formal neuropsychiatric testing assessment. The initial clinical evaluation and the recent clinical evaluation of the comparison. These included patients who eventually needed anticonvulsant and anti-behavioral medication, and patients were divided into “control group” and “improvement group” during the recent follow-up.