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目的:了解我院2010年儿童药品不良反应(ADR)发生情况,为临床合理用药提供参考。方法:回顾性统计分析我院2010年收集的90例儿童ADR报表。结果:发生ADR的药物以抗菌药最多见(76.39%),其次为中药注射剂(18.06%)。ADR累及的系统/器官以皮肤及其附件的损害最多见。90例ADR中,单一用药19例(21.11%),联合用药71例(78.89%)。90例ADR报表中给药途径均为静脉滴注。结论:应重视儿科临床ADR监测,临床医生应合理使用抗菌药及中药注射剂,以减少ADR的发生。
Objective: To understand the incidence of adverse drug reaction (ADR) in children in our hospital in 2010 and provide a reference for clinical rational drug use. Methods: A retrospective statistical analysis of 90 cases of ADR in our hospital collected in 2010. Results: ADR drugs were most commonly seen as antibacterials (76.39%), followed by traditional Chinese medicine injections (18.06%). Systems / organs affected by ADR are most commonly damaged by the skin and its appendages. Of 90 ADRs, 19 (21.11%) were single and 71 (78.89%) were combined. 90 ADR statements in the route of administration are intravenous drip. Conclusion: The pediatric clinical ADR monitoring should be emphasized. Clinicians should use antimicrobial agents and traditional Chinese medicine injections reasonably to reduce the occurrence of ADR.