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三七总皂苷(PNS)系从我国中药材三七Panax notoginseng(Burk)F.H.Chen的根茎中提取出来的主要药理成分,主要由人参皂苷Rg_1、Rb_1,三七皂苷R_1、R_2等40多种皂苷组成。三七总皂苷是中药三七的主要活性成分。近年研究表明,PNS可以调节细胞免疫炎症因子表达的作用,具有降低氧化应激、减轻炎症等作用。其能够减轻氧化型低密度脂蛋白(oxLDL)对内皮细胞的损伤,升高内皮细胞活性,降低内皮细胞免疫炎症因子白细胞分化抗原(CD40)、血管细
Panax notoginseng (PNS) is the main pharmacological component extracted from the rhizome of Chinese traditional medicine Panax notoginseng (Burk) FHChen, and is composed of more than 40 kinds of saponins such as ginsenoside Rg_1, Rb_1, notoginsenoside R_1, R_2, etc. composition. Panax notoginseng is the main active ingredient of Panax notoginseng. In recent years, studies have shown that PNS can regulate the role of cellular immune inflammatory factor expression, with reduced oxidative stress, reduce inflammation and so on. It can reduce oxidized low density lipoprotein (oxLDL) damage to endothelial cells, increase endothelial cell activity, reduce endothelial cell immune inflammatory factor leukocyte differentiation antigen (CD40), vascular thinning