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目的:分析清开灵注射液不良反应发生的原因,探讨其防治办法.方法:总结近年来清开灵注射液不良反应病例136例,分析不良反应的类型、临床特点及发生原因.结果:清开灵注射液所致的不良反应主要为Ⅰ型变态反应,其发生与患者的过敏史、中枢神经系统的原发病、药物静脉输注时的稀释浓度和合并用药相关.结论:应进一步研究清开灵注射液的成分及配方,减少不良反应.“,”Objective:To analyze the causes of the adverse reactions induced by Qingkailing injection and research the ways of prevention and treatment.Methods:This article summarized 136 cases of the adverse reactions caused by Qingkailing injection in recent years,analysed the category,the clinical characteristics and causes of the adverse reactions induced by Qingkailing injection.Results:The major adverse effects of Qingkailing injection were allergic reaction type Ⅰ,and were related to the allergic history and CNS diseases of the patient,diluted concentration of the drug,and other drugs combined with Qingkailing injection.Conclusion:The components and formula of Qingkailing injection should be studied in order to reduce the adverse reactions.