玻璃体内注射曲安奈德治疗糖尿病、视网膜静脉阻塞、葡萄膜炎等各种原因所致的黄斑水肿,显示出良好的临床效果和较为广泛的应用前景。减少血-视网膜屏障的破环,抑制花生四烯酸的途径,以及下调血管内皮生长因子可能是曲安奈德治疗黄斑水肿的作用机制。随着应用的日益广泛,其产生的并发症及黄斑水肿复发的现象不容忽视,因此,其长期疗效和安全性有待进一步研究。 Vitreous injection of triamcinolone acetonide in the treatment of diabetes, retinal vein occlusion, uveitis and other causes of macular edema, showing good clinical effect and a wider range of applications. Reducing the blood-retinal barrier disruption, inhibiting the arachidonic acid pathway, and downregulation of vascular endothelial growth factor may be the mechanism by which triamcinolone acetonide treats macular edema. With the increasingly wide range of applications, its complications and recurrence of macular edema can not be ignored, therefore, its long-term efficacy and safety needs further study.