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目的 :探讨丹参酮联合盐酸伐昔洛韦片治疗带状疱疹神经痛的临床效果。方法 :2012年9月到2015年2月选择在我院诊治的带状疱疹神经痛患者120例,根据随机数字表法分为治疗组与对照组各60例,对照组给予盐酸伐昔洛韦片治疗,治疗组给予丹参酮联合盐酸伐昔洛韦片治疗,治疗周期都为14d。结果 :治疗后经过观察,治疗组的有效率为98.3%,对照组为88.3%,治疗组的有效率高于对照组。治疗组的止疱时间、完全结痂时间和皮损痊愈时间明显少于对照组。两组治疗后的疼痛评分都均明显下降,与对照组相比,治疗后治疗组的疼痛评分明显较低。治疗期间,两组均无严重不良反应,与对照组相比,治疗组的感染、血肿、呕吐、腹胀等明显少于对照组。结论 :丹参酮联合盐酸伐昔洛韦片可以治疗带状疱疹,同时缓解患者神经痛,改善患者临床症状,提高总有效率,减少不良反应的发生。
Objective: To investigate the clinical effect of tanshinone combined with valacyclovir hydrochloride tablets in the treatment of herpes zoster neuralgia. Methods: From September 2012 to February 2015, 120 patients with herpes zoster diagnosed and treated in our hospital were selected and divided into treatment group (60 cases) and control group (60 cases) according to the random number table. The control group was given valacyclovir hydrochloride Treatment, the treatment group was given tanshinone valacyclovir hydrochloride tablets treatment, the treatment cycle was 14d. Results: After treatment, the effective rate of the treatment group was 98.3% and that of the control group was 88.3%. The effective rate of the treatment group was higher than that of the control group. The treatment group blister time, complete scab time and lesion recovery time was significantly less than the control group. Pain scores were significantly decreased after treatment in both groups, compared with the control group, the treatment group after treatment pain score was significantly lower. During treatment, there was no serious adverse reactions in both groups. Compared with the control group, the infection, hematoma, vomiting and bloating in the treatment group were significantly less than those in the control group. Conclusion: Tanshinone combined with valacyclovir hydrochloride tablets can treat herpes zoster, relieve neuralgia and improve clinical symptoms, improve the total effective rate and reduce the incidence of adverse reactions.