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东盟是亚太经合组织（ＡＰＥＣ）的创始成员，与该组织的其它成员在经济和政治上关系密切。东盟的ＡＰＥＣ政策经历了一个演变过程。东盟为维护自身的利益，要求ＡＰＥＣ保持松散性、协商性、非机构化等特点，使其对东盟具有更多的互补性而非竞争性。茂物会议后，东盟对ＡＰＥＣ实施贸易和投资自由化采取了更为合作的态度，但仍然保持强烈的独立决策意识，把东盟自由贸易区（ＡＦＴＡ）的利益放在首位。东盟作为正在崛起的次地区国家集团，在ＡＰＥＣ中发挥着独特的作用。
ASEAN is a founding member of the Asia-Pacific Economic Cooperation (APEC) and is closely linked economically and politically with the rest of the organization. ASEAN’s APEC policy has undergone an evolutionary process. In order to safeguard its own interests, ASEAN demanded that APEC should remain loose, consultative and non-institutionalized so as to make it more complementary to ASEAN than to compete with ASEAN. After the Bogor Conference, ASEAN took a more cooperative attitude toward the implementation of trade and investment liberalization by APEC. However, ASEAN maintained its strong sense of independence in decision-making and put the interests of the ASEAN Free Trade Area (AFTA) first. As a rising sub-regional group of countries, ASEAN plays a unique role in APEC.