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目的:探讨乳腺微小浸润癌的冰冻切片诊断方法与效果。方法:2015年10月至2016年10月选择在我院诊治的26例乳腺微小浸润癌患者作为研究对象,都进行冰冻切片单独检测、冰冻切片与快速免疫组化法联合检测。结果:所有患者均分离出前哨淋巴结,经冰冻切片法检测出前哨淋巴结癌转移者3例,转移率为11.54%;经冰冻切片与快速免疫组化法联合检测出前哨淋巴结癌转移者9例,转移率为34.62%,对比差异明显(P<0.05)。结论:乳腺微小浸润癌的冰冻切片诊断有一定的作用,通过多剖面、多点取材,可提高前哨淋巴结癌转移的检出率,有很好的应用价值。
Objective: To investigate the method and effect of frozen section diagnosis of breast micro-invasive carcinoma. Methods: From October 2015 to October 2016, 26 patients with micro-invasive breast cancer who were selected for diagnosis and treatment in our hospital were selected as the study objects. All the patients were examined by frozen sections and frozen section with rapid immunohistochemistry. Results: Sentinel lymph nodes were isolated from all the patients. Sentinel lymph node metastasis was detected by frozen section in 3 cases with metastasis rate of 11.54%. Nine cases of SLN metastasis were detected by frozen section and rapid immunohistochemistry. Transfer rate was 34.62%, the difference was significant (P <0.05). Conclusion: The diagnosis of breast micrometastasis in frozen section has a certain effect. It can improve the detection rate of sentinel lymph node metastasis through multi-section and multi-point drawing, which has a good application value.