空气可吸入颗粒物由于其粒径小、比表面积大、吸附性强、成分复杂等特点成为越来越受关注的空气污染物。近几年,颗粒物对肺外组织器官———心血管系统毒性机制的研究为人关注。该文主要从氧化应激、炎性损伤、血液系统损伤、自主神经系统失衡、心肌离子通道等方面对近20年大气颗粒物心血管毒性作用机制研究进行综述。 Due to its small particle size, large specific surface area, strong adsorptivity and complex composition, air respirable particulate matter (PM12) has become an increasingly popular air pollutant. In recent years, the study of particulate matter on extra-pulmonary organ tissue-cardiovascular system toxicity concerns. This review summarizes the mechanisms of cardiovascular toxicity of atmospheric particulate matter in recent 20 years from aspects of oxidative stress, inflammatory injury, blood system damage, autonomic nervous system imbalance and myocardial ion channels.