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在女性乳腺癌 ,尤其是家族性乳腺癌的发病机制与 BRCA- 1、BRCA- 2、myc、cerb B- 2、p53、PTEN和 AT基因等的突变、丢失或 DNA损害和修复中异常过程有关 ,了解这些基因学的变化将对防治乳腺癌有很大帮助
The pathogenesis of female breast cancer, especially familial breast cancer, is associated with abnormal processes in mutations, loss, or DNA damage and repair of BRCA-1, BRCA-2, myc, cerb B-2, p53, PTEN and AT genes, etc. , understanding these genetic changes will be of great help in preventing and treating breast cancer