【摘 要】
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A catalyst- and solvent-free protocol for the synthesis of 7-azagramine analogues is described via a three-component Mannich type reaction between 7-azaindole,
【机 构】
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School of Chemical Sciences, Solapur University,Department of Chemistry, A.S.P.College,
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
A catalyst- and solvent-free protocol for the synthesis of 7-azagramine analogues is described via a three-component Mannich type reaction between 7-azaindole, aromatic aldehydes and heterocyclic amines in acceptable to excellent yields. Structures of the compounds were confirmed satisfactorily by ~1H NMR, IR, mass, TOCSY, HSQC and HMBC spectral analyses.
A catalyst- and solvent-free protocol for the synthesis of 7-azagine analogues is described via a three-component Mannich type reaction between 7-azaindole, aromatic aldehydes and heterocyclic amines in acceptable to excellent yields. Structures of the compounds were confirmed satisfactorily by ~ 1H NMR, IR, mass, TOCSY, HSQC and HMBC spectral analyzes.
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