肺巨噬细胞在矽肺发生发展中具有重要的作用。迄今,已对巨噬细胞吞噬二氧化矽粉尘后的结构和功能改变进行了大量的实验研究,而对矽肺病人的巨噬细胞却研究得很少。作者根据单核细胞和组织巨噬细胞来自共同的骨髓造血细胞、它们的动力学和功能都归属于单核吞噬系统这一现代概念,采用细胞化学方法研究血液单核细胞酶的活性,以达了解各期矽肺病人单核巨噬细胞功能变化特点的目 Pulmonary macrophages play an important role in the development of silicosis. So far, a large number of experimental studies have been conducted on the structure and function changes of phagocytosed silica dust by macrophages, while few studies have been conducted on macrophages in patients with silicosis. Based on the common bone marrow hematopoietic cells derived from monocytes and tissue macrophages, their kinetics and function belong to the modern concept of a mononuclear phagocytic system. Cytochemical methods are used to study the activity of blood mononuclear cells to up to To understand the characteristics of mononuclear macrophages in patients with various stages of silicosis