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目的了解郑州地区不同肝病患者中ＴＴＶ（ｔｒａｎｓｆｕｓｉｏｎ ｔｒａｎｓｍｉｔｔｅｄ ｖｉｒｕｓ）感染状况及其临床特点。方法自行设计 ＴＴＶＯＲＦ１保守区的两对引物，对２０例非甲－庚型肝炎和９７例丙型肝炎患者血清进行ＰＣＲ检测，并对３０例资料完整的丙肝患者是否合并ＴＦＶ感染及其临床特点进行分析。结果丙型和非甲一庚型肝炎患者血清 ＴＴＶＤＮＡ检出率分别为 １６．５％（１６／９７）和 ２０％（４／ ２０）。结论郑州地区不同肝病患者中存在ＴＴＶ感染，但略低于安阳地区的检出率（３１．５８％），ＴＴＶ感染对慢性丙型肝炎患者临床表现、病程及肝功能指标无明显影响。
Objective To understand the status of TTV transfusion transmitted virus infection and its clinical features in patients with different liver diseases in Zhengzhou area. Methods Two pairs of primers of TTVORF1 conserved region were designed by ourselves. PCR was performed on the sera of 20 patients with non-hepatitis-A and 97 patients with hepatitis C, and 30 patients with complete HCV were infected with TFV infection and their clinical features were analyzed analysis. Results The detection rates of serum TTVDNA in patients with non-hepatitis A and hepatitis C were 16.5% (16/97) and 20% (4/20) respectively. Conclusion TTV infection exists in different liver disease patients in Zhengzhou, but slightly lower than that in Anyang (31.58%). TTV infection has no significant effect on clinical manifestations, duration of disease and liver function in chronic hepatitis C patients.