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目的探讨肝炎后肝硬化患者心电图改变与Child-Pugh分级及预后的相关性。方法选择本院诊治的146例肝炎后肝硬化患者,按照Child-Pugh评分对其进行分级;同时采集患者体表心电图,并测量计算QTc,记录各种心电图异常表现。结果患者心电图异常改变率62.33%,显著高于慢性肝炎组,且随Child-Pugh分级增加而升高(P<0.05);异常心电图以Q-T间期延长为主(占56.85%),QTc值与Child-Pugh分级存在相关性(P<0.05);心电图异常组和正常组患者病死率差异有统计学意义(P<0.05)。结论肝炎后肝硬化患者心电图改变与Child-Pugh分级及预后密切相关。
Objective To investigate the relationship between ECG changes and Child-Pugh classification and prognosis in patients with posthepatitic cirrhosis. Methods 146 patients with posthepatitic cirrhosis who were diagnosed and treated in our hospital were selected and graded according to Child-Pugh score. At the same time, the body surface electrocardiogram (ECG) was measured and QTc was measured to record abnormal ECG findings. Results The abnormal rate of electrocardiogram in patients was 62.33%, significantly higher than that in chronic hepatitis group and increased with Child-Pugh classification (P <0.05). The abnormal ECG was mainly QT prolongation (56.85%), QTc value was Child-Pugh grade correlation (P <0.05). There was significant difference in mortality between patients with ECG abnormalities and normal controls (P <0.05). Conclusion The changes of ECG in patients with posthepatitic cirrhosis are closely related to Child-Pugh classification and prognosis.