论文部分内容阅读
目的研究双唑泰栓与乳酸杆菌联合治疗非特异性阴道炎的疗效。方法选择来宾市中医医院2013年1月至2013年12月妇科门诊就诊的126例非特异性阴道炎患者,采用数字表随机法分为两组,每组63例,对照组给予双唑泰栓治疗,研究组在对照组的基础上加用乳酸杆菌,疗程结束后7 d和28 d复查评价疗效。结果两组治疗后阴道清洁度与p H值均较治疗前明显改善,研究组p H<4.5,阴道清洁度Ⅰ~Ⅱ的构成比例分别达95.24%和96.83%,明显高于对照组,两组比较差异有统计学意义(P<0.05)。两组治疗后临床症状体征包括阴道充血、白带增多及外阴痒痛症状较治疗前明显改善,与治疗前比较差异有统计学意义(P<0.05)。两组临床症状体征改善情况比较差异无统计学意义(P>0.05)。研究组总有效率为95.24%,对照组为79.37%,研究组明显高于对照组;研究组复发率为1.59%,对照组为11.11%,两组比较差异均有统计学意义(P<0.05)。结论乳酸杆菌可改善阴道内环境,提高阴道清洁度,联合双唑泰栓使治疗效果明显地提高。
Objective To study the efficacy of combination of metronidazole and lactobacillus in the treatment of nonspecific vaginitis. Methods A total of 126 non-specific vaginitis patients from the gynecology clinic of Chinese Medicine Hospital of Laibin Hospital from January 2013 to December 2013 were randomly divided into two groups (n = 63 each). Patients in the control group were treated with oxazolone , The research group added Lactobacillus on the basis of the control group, and evaluated the efficacy on the 7th and 28th days after the end of treatment. Results After treatment, the vaginal cleanliness and p H value of both groups were significantly improved compared with that before treatment. The p H <4.5 and the cleanliness Ⅰ ~ Ⅱ of the study group were 95.24% and 96.83%, respectively, which were significantly higher than those of the control group The difference was statistically significant (P <0.05). Symptoms and signs of both groups after treatment, including vaginal congestion, vaginal discharge and genital itching pain symptoms significantly improved compared with before treatment, compared with before treatment was statistically significant (P <0.05). The improvement of clinical symptoms and signs between the two groups showed no significant difference (P> 0.05). The total effective rate was 95.24% in the study group and 79.37% in the control group, which was significantly higher in the study group than in the control group. The recurrence rate was 1.59% in the study group and 11.11% in the control group, with significant difference between the two groups (P <0.05) ). Conclusion Lactobacillus can improve vaginal environment, improve vaginal cleanliness, combined with double-azole Thai suppository treatment effect was significantly improved.