论文部分内容阅读
目的观察分析老年2型糖尿病(T2DM)采用胰岛素泵治疗的效果。方法选取我院收治的48例老年T2DM患者,双盲法随机分为观察组和对照组,对照组采用皮下注射诺和灵N或诺和灵RZ治疗,观察组采用胰岛素泵持续皮下泵入诺和灵R治疗。分别观察记录两组患者治疗1个月、3个月的空腹及餐后2h血糖、胰岛素的用量、低血糖发生率、HbAlc、胰岛素分泌指数。结果治疗1个月两组患者均能达到血糖的控制目标。观察组的血糖达标时间明显少于对照组(P<0.01),胰岛素平均用量、空腹时血糖、餐后2h的血糖均优于对照组(P<0.05);治疗3个月后观察组的胰岛素用量、低血糖发生率明显低于对照组(P<0.05),胰岛素的分泌指数明显优于对照组(P<0.05)。两组HbAlc水平差异无统计学意义(P>0.05)。结论胰岛素泵的强化治疗是老年T2DM患者安全有效的治疗方法,值得在临床上推广应用。
Objective To observe and analyze the effect of insulin pump therapy on senile type 2 diabetes mellitus (T2DM). Methods Forty-eight elderly patients with T2DM admitted to our hospital were randomly divided into observation group and control group by double-blind method. The control group was treated with norepinephrine N or Novolin RZ subcutaneously. The observation group was subcutaneously injected with insulin pump And spiritual R treatment. Two groups of patients were observed for 1 month, 3 months fasting and 2h postprandial blood glucose, insulin dosage, incidence of hypoglycemia, HbAlc, insulin secretion index. Results One month after treatment, the control target of blood glucose was reached in both groups. The observation group’s blood glucose standard time was significantly less than that of the control group (P <0.01). The average insulin dosage, fasting blood glucose and postprandial blood glucose 2h were better than the control group (P <0.05) Dosage, the incidence of hypoglycemia was significantly lower than the control group (P <0.05), insulin secretion index was significantly better than the control group (P <0.05). HbAlc levels between the two groups showed no significant difference (P> 0.05). Conclusion The intensive treatment of insulin pump is a safe and effective treatment for elderly patients with T2DM, which is worth popularizing in clinic.