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The hydrophilic, macroporous and beaded ternary copolymer of glycidyl methacrylate (GMA)/methacrylamide(MA)/N,N′-methylene-bis(acrylamide)(MBAA)was synthesized using the industrial agents by inverse suspension polymerization. The apparent activity of the immobilized penicillin G acylase reached 1096 IU/g for hydrolysis penicillin G on the beads with diameter of 0.11-0.13 mm, and it changed hardly after 50 cycles. It can be expected to be a good potential in industrial application.
The hydrophilic, macroporous and beaded ternary copolymer of glycidyl methacrylate (GMA) / methacrylamide (MA) / N, N’-methylene-bis (acrylamide) (MBAA) was synthesized using the industrial agents by inverse suspension polymerization. immobilized penicillin G acylase reached 1096 IU / g for hydrolysis penicillin G on the beads with diameter of 0.11-0.13 mm, and it had changed hardly hardly after 50 cycles. It can be expected to be a good potential in industrial application.