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[摘要] 目的 观察分析腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征后的妊娠情况。 方法 选取2015年1～12月于我院就诊的多囊卵巢综合征患者130例，采用随机数字法将患者均分为联合组（n=65）与药物组（n=65），联合组患者给予腹腔镜卵巢打孔联合达英-35治疗，药物组患者仅给予达英-35治疗，对比两组患者的治疗效果。结果 两组患者治疗前的血清性激素水平差异无统计学意义（P>0.05）；两组患者治疗后的T、LH水平低于治疗前（P<0.05），且联合组患者治疗后的T、LH水平低于药物组（P<0.05）；联合组患者的妊娠率、足月分娩率显著高于对照组（P<0.05）。 结论 腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征的临床疗效良好，可有效降低T、LH水平，治疗后患者的妊娠率及足月分娩率较高，是治疗多囊卵巢综合征后妊娠的有效方法之一。
[关键词] 多囊卵巢综合征后妊娠；腹腔镜卵巢打孔术；达英-35；分娩
[中图分类号] R711 [文献标识码] B [文章编号] 1673-9701（2017）15-0052-03
[Abstract] Objective To observe and analyze the laparoscopic ovarian puncture combined with Diane-35 in the treatment of pregnancy after polycystic ovary syndrome. Methods A total of 130 patients with polycystic ovary syndrome treated in our hospital from January to December 2015 were chosen and randomly divided into the combined group（n=65） and the drug group（n=65） according to the digital random method. The patients in the combined group were treated with laparoscopic ovarian perforation combined with Diane-35 treatment. The patients in the drug group were treated with Diane-35 only. And the therapeutic effect was compared between the two groups. Results There was no significant difference in serum sex hormone level between the two groups before treatment（P>0.05）. The levels of T and LH in the two groups after treatment were lower than those before treatment， and the levels of T and LH in the combined group were lower than those in drug group（P<0.05）. The pregnancy rate and full-term delivery rate of the combined group were significantly higher than those of the drug group（P<0.05）. Conclusion Laparoscopic ovarian perforation combined with Diane-35 has a good clinical effect in the treatment of polycystic ovary syndrome， which can effectively reduce the level of T and LH. The pregnancy rate and full-term delivery rate of patients after treatment are higher. The combined treatment is one of the effective treatment methods for pregnancy after polycystic ovary syndrome.
[Key words] Pregnancy after polycystic ovary syndrome； Laparoscopic ovarian perforation； Diane-35； Childbirth
多囊卵巢綜合征是常见的妇科内分泌疾病之一，是一种生殖功能障碍与糖代谢异常并存的内分泌紊乱综合征，发病率较高，临床症状主要表现为月经紊乱、多卵泡不成熟、闭经、肥胖及不孕，严重影响患者的生活质量，临床上需提高重视[1]。腹腔镜卵巢打孔术是治疗多囊卵巢综合征后妊娠的常用手术方式，达英-35是常用药物治疗方式[2]。本研究分析腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征后妊娠的临床疗效，以期为临床治疗提供参考依据，现报道如下。
1 资料与方法
1.1 一般资料
选取2015年1～12月于我院就诊的多囊卵巢综合征患者130例，所有患者均符合多囊卵巢综合症的诊断标准，采用数字随机法将患者均分为联合组（n=65）与药物组（n=65）。联合组：年龄22～41岁，平均（32.24±3.28）岁；病程2个月～13年，平均（3.74±1.25）年；BMI指数（28.95±1.32）kg/m2。药物组：年龄23～41岁，平均（33.08±3.72）岁；病程3个月～13年，平均（3.48±1.05）年；BMI指数（28.68±1.29）kg/m2。两组患者在年龄、病程、BMI指数等一般资料方面对比差异无统计学意义（P>0.05），具有可比性。 1.2 治疗方法
药物组患者仅给予达英-35治疗，具体为：达英-35[Schering GmbH
[关键词] 多囊卵巢综合征后妊娠；腹腔镜卵巢打孔术；达英-35；分娩
[中图分类号] R711 [文献标识码] B [文章编号] 1673-9701（2017）15-0052-03
[Abstract] Objective To observe and analyze the laparoscopic ovarian puncture combined with Diane-35 in the treatment of pregnancy after polycystic ovary syndrome. Methods A total of 130 patients with polycystic ovary syndrome treated in our hospital from January to December 2015 were chosen and randomly divided into the combined group（n=65） and the drug group（n=65） according to the digital random method. The patients in the combined group were treated with laparoscopic ovarian perforation combined with Diane-35 treatment. The patients in the drug group were treated with Diane-35 only. And the therapeutic effect was compared between the two groups. Results There was no significant difference in serum sex hormone level between the two groups before treatment（P>0.05）. The levels of T and LH in the two groups after treatment were lower than those before treatment， and the levels of T and LH in the combined group were lower than those in drug group（P<0.05）. The pregnancy rate and full-term delivery rate of the combined group were significantly higher than those of the drug group（P<0.05）. Conclusion Laparoscopic ovarian perforation combined with Diane-35 has a good clinical effect in the treatment of polycystic ovary syndrome， which can effectively reduce the level of T and LH. The pregnancy rate and full-term delivery rate of patients after treatment are higher. The combined treatment is one of the effective treatment methods for pregnancy after polycystic ovary syndrome.
[Key words] Pregnancy after polycystic ovary syndrome； Laparoscopic ovarian perforation； Diane-35； Childbirth
多囊卵巢綜合征是常见的妇科内分泌疾病之一，是一种生殖功能障碍与糖代谢异常并存的内分泌紊乱综合征，发病率较高，临床症状主要表现为月经紊乱、多卵泡不成熟、闭经、肥胖及不孕，严重影响患者的生活质量，临床上需提高重视[1]。腹腔镜卵巢打孔术是治疗多囊卵巢综合征后妊娠的常用手术方式，达英-35是常用药物治疗方式[2]。本研究分析腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征后妊娠的临床疗效，以期为临床治疗提供参考依据，现报道如下。
1 资料与方法
1.1 一般资料
选取2015年1～12月于我院就诊的多囊卵巢综合征患者130例，所有患者均符合多囊卵巢综合症的诊断标准，采用数字随机法将患者均分为联合组（n=65）与药物组（n=65）。联合组：年龄22～41岁，平均（32.24±3.28）岁；病程2个月～13年，平均（3.74±1.25）年；BMI指数（28.95±1.32）kg/m2。药物组：年龄23～41岁，平均（33.08±3.72）岁；病程3个月～13年，平均（3.48±1.05）年；BMI指数（28.68±1.29）kg/m2。两组患者在年龄、病程、BMI指数等一般资料方面对比差异无统计学意义（P>0.05），具有可比性。 1.2 治疗方法
药物组患者仅给予达英-35治疗，具体为：达英-35[Schering GmbH