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目的比较小儿氯胺酮麻醉前如何用药,才能更好地避免患儿术前的恐惧和哭闹不安。方法选择1～8岁手术患儿90例,随机分为三组。A组:30例,咪唑安定0.2 mg/kg鼻注;B组:30例,咪唑安定0.1 mg/kg肌注;C组:30例,术中静注0.05 mg/kg。观察用药前后的镇静程度、遗忘效果以及氯胺酮麻醉前后的血压(BP)、心率(HR)、呼吸(RR)、脉搏血氧饱和度(SpO2)的变化。结果咪唑安定鼻注与肌注效果无显著差异,但鼻注优于肌注,同时两者明显优于术中静注咪唑安定。
Objective To compare pediatric ketamine anesthesia before medication, in order to better avoid preoperative children with fear and crying uneasiness. Methods Ninety children aged 1 ~ 8 years old were randomly divided into three groups. Group A: 30 cases, midazolam 0.2 mg / kg; Group B: 30 cases, midazolam 0.1 mg / kg intramuscular injection; Group C: 30 cases, intraoperative intravenous injection of 0.05 mg / kg. The degree of sedation, amnesia and the changes of blood pressure (BP), heart rate (HR), respiration (RR) and pulse oxygen saturation (SpO2) before and after ketamine anesthesia were observed before and after treatment. Results Midazolam and intramuscular injection of no significant difference, but better than the intramuscular injection of nasal injection, both significantly better than intraoperative intravenous midazolam.