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Apollon是近年来新发现的凋亡抑制因子,具有广泛的生物学作用,有研究发现Apollon在多种肿瘤中表达明显升高,可能与肿瘤的发生与预后有关,但具体参与机制仍不明确。本文就Apollon在人脑胶质瘤中的生物学特性方面的研究进展做一综述。
Apollon is a newly discovered inhibitor of apoptosis in recent years. It has a wide range of biological effects. Apollon has been found to be significantly upregulated in many tumors, which may be related to tumorigenesis and prognosis. However, its mechanism of participation is still unclear. This article reviews Apollon 's biological properties in human gliomas.