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目的:观察血透对慢性肾功能衰竭患者血浆纤维蛋白原的影响。方法:纤维蛋白原采用计算机自动检测系统,D-二聚体采用ELISA法,FDP采用纸片凝集法。结果:20例慢性肾功能衰竭透析前、后各项数值分别为:FMPV 0.569±0.130,0.680±0.150;Amax 0.281±0.055,0.345±0.065;S(g/L)3.15±0.70,3.98±0.85;DT(S)15±3,20±4;FMDV/Amax 2.024,1.971;D-二聚体(mg/L)0.905,0.995;FDP(mg/L)6.06,6.76;结论:慢性肾功能衰竭患者血浆中纤维蛋白原水平、功能及纤溶活力均高于正常对照,血透后各项指标不能改善甚至仍有上调。
Objective: To observe the effect of hemodialysis on plasma fibrinogen in patients with chronic renal failure. Methods: Fibrinogen was detected by computer, D-dimer was detected by ELISA, and FDP was by paper agglutination. Results: The values of FMPV before and after dialysis in 20 patients with chronic renal failure were: FMPV 0.569 ± 0.130,0.680 ± 0.150; Amax 0.281 ± 0.055,0.345 ± 0.065; S (g / L) 3.15 ± 0.70,3.98 ± 0.85; DT (S) 15 ± 3,20 ± 4; FMDV / Amax 2.024,1.971; D-dimer 0.905,0.995; FDP mg / L 6.06,6.76; Conclusion: Patients with chronic renal failure Plasma fibrinogen levels, function and fibrinolytic activity were higher than the normal control, hemodialysis after the index can not be improved or even still up.