对于原发性纤毛活动障碍(PCD)的研究自1975年有不少报导,包括对 Kartagener 综合征的研究,发现病人呼吸道清除功能不良及精子活动障碍与其纤毛和精子轴丝先天性缺陷有关。约50%伴有内脏逆转,即 Kartagener 综合征。作者为阐明此类病人与正常人纤毛结构的不同,对下列三组人群进行鼻粘膜纤毛超微结构的研究。1.Kartagener 综合征13例;2.因过敏、囊样纤维病变和免疫紊乱等原因引起的 Studies of primary ciliary movement disorders (PCD) have been reported since 1975, including studies of Kartagener’s syndrome and found that patients with respiratory tract dysfunction and sperm motility disorders are associated with congenital defects in their cilia and sperm axis. About 50% with visceral reversal, the Kartagener syndrome. In order to elucidate the difference between these patients and normal cilia, the authors studied the ultrastructure of nasal mucociliary in the following three groups. 1. Kartagener syndrome in 13 cases; 2. due to allergies, cystic fibrosis and immune disorders and other causes