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本文利用离体组织灌流技术,对刺激家兔颈上神经节内壁交感神经引起兔耳中央动脉收缩的本质进行探讨,α受体拮抗剂仅部分阻断跨壁神经刺激(TNS)引起的收缩,若预先使用利血平耗竭离体血管内源性儿茶酚胺,由TNS引起的此种家兔耳中央动脉收缩则明显减弱,与此同时,α受体拮抗剂却增强了后期(residual)收缩反应,这种增强作用可能是因突触前膜α受体同时被阻断而引起,由此可见,交感神经冲动引起的家兔耳中央动脉收缩绝大部分是由去甲肾上腺素(NE)介导的,但后期收缩反应则可能是由另一种不明递质所介导,而这种属于外周循环系统的耳动脉交感神经与血管之间冲动传递方式又有别于大脑动脉的传递方式。
In this study, the in vitro tissue perfusion technique was used to investigate the nature of contracting the central nervous system of the rabbit ear through sympathetic stimulation of the inner cervical sympathetic nerve in rabbits. The α receptor antagonist partially blocked the contraction induced by transmural nerve stimulation (TNS) If pre-use of reserpine depleted endogenous catecholamines in vitro, the contractions of the central auricular ear of these rabbits caused by TNS were significantly attenuated, while α-receptor antagonists increased the residual contractile response, This enhancement may be due to pre-synaptic membrane α receptor was blocked at the same time, we can see that sympathetic nerve impulses caused by rabbit ear central artery contraction mostly by norepinephrine (NE) -mediated , But the latter part of the contractile response may be mediated by another unknown transmission, and this belongs to the peripheral circulation system of the ear artery between the sympathetic nerve and vascular impulse transfer method is different from the cerebral artery delivery.