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目的:探讨慢性支气管炎急性加重期采用莫西沙星治疗临床效果。方法:本次共选择慢性支气管炎100例患者,均为我院呼吸内科2012年1月至2014年1月收治,随机分组,就阿莫西林治疗(对照组,n=50)与莫西沙星治疗(观察组,n=50)效果进行比较。结果:观察组选取病例临床总有效率为94%,明显高于对照组82%,差异有统计学意义(P<0.05)。观察组经统计示流感嗜血杆菌、铜绿假单孢菌、肺炎链球菌、副流感嗜血杆菌等清除率为88%,对照组为76%,无明显差异(P>0.05),两组均无严重不良反应性发生。结论:慢性支气管炎急性加重采用莫西沙星治疗,可显著改善预后,保障患者生存质量。
Objective: To investigate the clinical effect of moxifloxacin in acute exacerbation of chronic bronchitis. Methods: A total of 100 patients with chronic bronchitis were selected. All of them were admitted to Department of Respiratory Medicine in our hospital from January 2012 to January 2014 and were randomly divided into four groups: amoxicillin treatment group (n = 50) and moxifloxacin Treatment (observation group, n = 50) were compared. Results: The total effective rate of the selected cases in the observation group was 94%, which was significantly higher than that in the control group (82%) (P <0.05). In the observation group, the clearance rates of Haemophilus influenzae, Pseudomonas aeruginosa, Streptococcus pneumoniae and Haemophilus parainfluenza were 88% in the observation group and 76% in the control group (P> 0.05) No serious adverse reactions occurred. Conclusion: Acute exacerbation of chronic bronchitis with moxifloxacin treatment can significantly improve the prognosis and ensure the quality of life of patients.