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目的:探讨室壁瘤形成与冠状动脉粥样硬化的关系,以及室壁瘤对心室功能的影响。方法:采用冠状动脉造影方法对168例临床疑诊冠心病患者进行检查。结果:发现室壁瘤26例,其中冠状动脉单支病变11例,双支7例,三支7例,冠状动脉正常1例,受累血管狭窄程度均在Ⅲ级以上。室壁瘤累及心室壁一段、二段、三段及四段的左室射血分数分别平均为(50±31)%、(32±16)%、(29±21)%及(18±14)%(r=-0.65,P<0.05)。结论:室壁瘤的发生与冠状动脉受累程度明显相关,室壁瘤的范围愈大,左室射血功能障碍愈明显。
Objective: To investigate the relationship between the formation of aneurysm and coronary atherosclerosis and the effect of ventricular aneurysm on ventricular function. Methods: 168 cases of coronary heart disease were examined by coronary angiography. Results: 26 cases of aneurysm were found, including 11 cases with single coronary artery disease, 7 cases with double branch, 7 cases with three branches and 1 case with normal coronary artery. The degree of involved vascular stenosis was above grade Ⅲ. The mean left ventricular ejection fraction (LVEFs) of aneurysm involving the ventricular wall in the first, second, third and fourth segments were (50 ± 31)%, (32 ± 16)%, (29 ± 21)% and (18 ± 14) )% (r = -0.65, P <0.05). Conclusion: The incidence of aneurysm is related to the extent of coronary artery involvement. The larger the extent of aneurysm, the more obvious is the left ventricular ejection dysfunction.