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我院从1989～1996年共收治急性白血病(AL)78例,其中51例相继发生肺部感染。AL并发肺部的感染可加重白血病的症状甚至危及生命,在临床治疗中十分困难。我们对51例合并肺部感染的AL患者进行了临床分析,现报道如下。1 资料与结果1.1 一般资料 51例患者发生肺部感染均符合下列条件:①骨髓细胞学检查确诊为AL(M_119例、M_213例、M_38例、急淋11例)。②人院后出现发热、呼吸系统症状和体征。③X线检查有肺部炎性改变。出现肺部感染的时间为3～20天。年龄16～67岁。男23例,女28例。全部患者人院后均分别给予COAP、HOAP、DA、VP等方案治疗。全部患者均有不同程度的发热,体温38.1～39.6℃。咳嗽46例占91％,胸部发闷不适18例占25％,吐痰32例占64％,肺部听诊有干湿性啰音16例,占31％。
In our hospital, 78 cases of acute leukemia (AL) were treated from 1989 to 1996, of which 51 cases had subsequent lung infections. The infection of AL with pulmonary disease can aggravate the symptoms of leukemia and even endanger life. It is very difficult in clinical treatment. We performed a clinical analysis of 51 AL patients with pulmonary infections, which are reported below. 1 data and results 1.1 General Information 51 cases of patients with lung infections were in line with the following conditions: 1 bone marrow cytology confirmed as AL (M_119 cases, M_213 cases, M_38 cases, 11 cases of acute shower). Two people had fever, respiratory symptoms and signs after the hospital. 3 X-ray examination showed lung inflammatory changes. The time of lung infection is 3 to 20 days. Age 16 to 67 years old. There were 23 males and 28 females. All patients were treated with COAP, HOAP, DA, and VP after hospitalization. All patients have different degrees of fever, body temperature 38.1 ~ 39.6 °C. Cough occurred in 91 cases (91%), chest discomfort in 18 cases (25%), spitting in 32 cases (64%), and pulmonary auscultation with dry and wet rales in 16 cases (31%).