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目的:评价抗病毒合剂与奥司他韦联用对流行性感冒患儿的临床疗效。方法:采用回顾性分析法,选取2015年6月—2016年4月期间收治的流行性感冒患儿80例的临床资料,采用随机数字表法将患儿分为观察组40例和对照组40例;对照组患儿给予奥司他韦治疗,观察组患儿在对照组基础上加用抗病毒合剂治疗,比较两组患儿治疗后的总有效率和不良反应的发生率。结果:观察组患儿治疗后的总有效率为95.00%高于对照组为80.00%(P<0.05),体温复常时间、鼻塞流涕好转时间、治疗时间以及咽红肿痛复常时间均优于对照组(P<0.05),不良反应的发生率为7.5%低于对照组为30.0%(P<0.05)。结论:采用抗病毒合剂与奥司他韦联用治疗小儿流行性感冒患儿,临床疗效较为显著,不良反应较低,有利于患儿的康复。
Objective: To evaluate the clinical efficacy of anti-viral combination and oseltamivir in the treatment of children with influenza. Methods: The clinical data of 80 children with influenza were collected from June 2015 to April 2016 by retrospective analysis. The children were divided into observation group (40 cases) and control group (40) by random number table Cases; control group children given oseltamivir treatment, the observation group children in the control group based on the use of antiviral combination therapy, the two groups of children after treatment, the total effective rate and incidence of adverse reactions. Results: The total effective rate of the observation group was 95.00%, which was higher than that of the control group (80.00%) (P <0.05). The body temperature recovery time, the time of the stuffy nose runny, the treatment time and the time of recurrence of pharyngitis, (P <0.05). The incidence of adverse reactions was 7.5% lower than that of the control group (30.0%, P <0.05). Conclusion: The combination of antiviral agent and oseltamivir in the treatment of infantile influenza in children, the clinical efficacy is more significant, lower adverse reactions, is conducive to the rehabilitation of children.