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目的:探讨Solitaire AB支架取栓联合动脉溶栓治疗急性缺血性脑卒中的临床疗效。方法:收集2014年8月至2016年8月我院收治的15例急性缺血性脑卒中患者,进行Solitaire AB支架取栓联合动脉溶栓治疗,通过评价患者治疗前后的美国国立卫生研究院卒中量表评分(NIHSS评分)比较治疗效果,通过评价患者随访期间的改良Rankin评分(m RS)和哥拉斯哥昏迷评分(GCS)比较预后情况。结果:15例患者通过动脉溶栓联合1~3次Solitaire AB取栓后,14例患者均达到部分或完全再通,1例患者因生命体征不稳而终止取栓手术,再通率为93.3%。患者出院时NIHSS评分为(4.33±1.45),显著低于术前的(12.93±4.25)(P<0.05)。15例患者均通过3个月的术后随访,改良Rankin(m RS)评分均显示良好,其中2例为2分,5例为1分,8例为0分。所有患者均未发生血管再闭塞等相关并发症。结论:Solitaire AB支架取栓联合动脉溶栓治疗急性缺血性脑卒中的临床效果良好且安全性高。
Objective: To investigate the clinical effect of Solitaire AB stent thrombectomy combined with arterial thrombolysis in the treatment of acute ischemic stroke. METHODS: Fifteen patients with acute ischemic stroke who were admitted to our hospital from August 2014 to August 2016 were enrolled in this study. They were treated with Solitaire AB stent thrombolysis combined with arterial thrombolysis. Assessments were made before and after treatment with the National Institutes of Health Stroke Scores were scored (NIHSS score) to compare treatment outcomes, and prognosis was assessed by evaluating improved Rankin score (m RS) and Glasgow Coma Scale (GCS) during patient follow-up. Results: Fifteen patients received partial or complete recanalization after arterial thrombolysis combined with Solitaire AB thrombolysis 1 to 3 times. One patient stopped taking thrombectomy due to unstable vital signs, and the recanalization rate was 93.3 %. The NIHSS score at discharge was (4.33 ± 1.45), significantly lower than preoperative (12.93 ± 4.25) (P <0.05). All 15 patients were followed up for 3 months. The improved rankin (m RS) scores were all good, including 2 in 2 patients, 1 in 5 patients and 0 in 8 patients. No complications such as vascular reocclusion occurred in all patients. Conclusion: Solitaire AB stent thrombectomy combined with arterial thrombolysis in the treatment of acute ischemic stroke has good clinical effect and high safety.