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目的探讨健脾益气、活血化瘀、清热解毒法对肿瘤的预防和治疗效果。方法选择补气、活血、解毒及合剂组药物,进行动物实验,分别观察对S_(180)小鼠的抑瘤情况、生存状况、脾重变化等以及对HepA 小鼠生存期的影响。结果合剂组(参芪蟅虫汤)抑瘤作用最好,其次为活血化瘀组( P< 0. 01)。合剂组延长 HepA小鼠生存期最长( P< 0. 01),其次为解毒组。结论中医健脾益气、活血化瘀、清热解毒三法综合应用防治肿瘤具有明显优势,其疗效好于单法应用。
Objective To explore the preventive and therapeutic effects of spleen-enriching qi, promoting blood circulation, clearing away heat and removing toxic substances on tumors. Methods Animals were supplemented with qi, blood, detoxification, and drug combinations. Animal experiments were performed to observe the effects of tumor growth, survival status, and spleen weight changes on the survival rate of HepA mice. Results The best anti-tumor effect was found in the mixture group (Shenqi worm soup), followed by the blood circulation group (P<0. 01). In the mixture group, the survival time of HepA mice was the longest (P<0.01), followed by the detoxification group. Conclusion The three methods of traditional Chinese medicine, spleen Qi, promoting blood circulation, resolving blood stasis, clearing heat and detoxifying, have obvious advantages in preventing and treating cancer, and its curative effect is better than single method application.