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目的探讨老年人药源性心律失常。方法收集临床资料,部分为个案,采用自身配对、治疗前后比较等方法观察药源性因素引起心律失常情况。结果药源性因素引起心律失常的药物有洋地黄、阿托品、庆大霉素、头孢霉素、青霉素、喹诺酮、西沙比利、西洛他唑、抗肿瘤药、抗精神病药等,可引起各种类型心律失常。结论相关药物可引起多种心律失常,机制是药物对心脏直接和间接损害有关。有效、合理用药可预防药源性心律失常。
Objective To investigate the drug-induced arrhythmia in the elderly. Methods The clinical data were collected, some of them were individual cases. The self-matching and the comparison before and after treatment were used to observe the drug-induced cardiac arrhythmia. Results drug-induced cardiac arrhythmia drugs are digitalis, atropine, gentamicin, cephamycin, penicillin, quinolone, cisapride, cilostazol, anti-tumor drugs, antipsychotics, etc., can cause A type of arrhythmia. Conclusion The related drugs can cause a variety of arrhythmia, the mechanism is the drug on the heart of direct and indirect damage related. Effective and reasonable medication can prevent drug-induced arrhythmia.