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目的 :将阿奇霉素、红霉素治疗小儿支原体肺炎 (MPP)不同疗法、疗效进行对比分析。方法 :采用随机分组方法 ,将 15 0例患儿分为A组 (阿奇霉素转换治疗组 )、B组 (阿奇霉素静脉给药组 )、C组 (红霉素组 ) 3组 ;每组 5 0例。用临床试验的方法 ,比较三组间的显效率、治愈率、总有效率、住院时间、治疗费用及不良反应发生率。结果 :组间两两比较 ,除A、B组与C组显效率比较有显著差异 (P <0 0 5 ) ,以A、B两组为高 ;其他组间显效率、治愈率、总有效率两两比较均无显著差异 (P >0 0 5 )。住院天数、治疗费用经方差分析 ,A组与B、C组间有显著性差异 ( P <0 0 1) ,以A组费用最低。不良反应发生率组间比较A、B组与C组均有显著性差异 (P <0 0 5 ) ,以A、B组为低。结论 :阿奇霉素早期转换治疗支原体肺炎 ,具有疗效好、痛苦少、费用低、住院时间短、减少院内感染等优点 ,有明显的成本效益优势 ,值得临床应用
OBJECTIVE: To compare and analyze the different therapies and curative effects of azithromycin and erythromycin in children with mycoplasma pneumonia (MPP). Methods: A total of 150 children were divided into group A (azithromycin conversion treatment group), group B (azithromycin intravenous group) and group C (erythromycin group) by randomized grouping method. Fifty cases in each group . Clinical trial methods were used to compare the three groups of significant efficiency, cure rate, total effective rate, hospital stay, treatment costs and incidence of adverse reactions. Results: There was a significant difference (P <0.05) in the efficiency of group A, B between group A and group B, and between group A and group B; There was no significant difference in efficiency between any two groups (P> 0.05). Hospitalization days, treatment costs by analysis of variance, A group and B, C were significantly different (P <0 01), the lowest cost in the A group. The incidence of adverse reactions between groups A, B group and C group were significantly different (P <0 05), A, B group is low. Conclusion: Azithromycin early conversion treatment of mycoplasma pneumonia, with good effect, less pain, low cost, shorter hospital stay, reduce nosocomial infections, etc., has obvious cost-effectiveness advantage, it is worth clinical application