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糖尿病神经病变(diabetic neuropathy,DN)是糖尿病常见的并发症,患病率约为50%[1],其发病机制复杂,涉及激活众多通路神经生长因子[2]、炎性反应介质[3]及活性氧和氮等方面,现已成为糖尿病患者致残、致死的主要原因。聚腺苷酸二磷酸核糖聚合酶-1
Diabetic neuropathy (DN) is a common complication of diabetes with a prevalence of about 50% [1]. Its pathogenesis is complex and involves activating many pathways of nerve growth factor [2] and inflammatory mediators [3] And reactive oxygen species and nitrogen, etc., has become the main cause of disability and death of diabetic patients. Polyadenyl diphosphate ribose polymerase-1