近年来,放射配体技术的应用及离体心肌细胞的培养观察试验,均已证明了心肌上有α—肾上腺素能受体(以下简称α受体)。并对其功能进行了广泛的研究。早在1953年,Leimdorfer首先报道了α受体阻滞剂酚妥拉明具有抗心律失常作用。当前,人们对心脏α受体及α受体阻滞剂抗心律失常机制的研究已取得一些进展,本文拟就此作一综述。 In recent years, the application of radioligand technology and cultured cells in vitro observation and testing have been shown to have α-adrenergic receptor (hereinafter referred to as α receptor). And conducted extensive research on its functions. As early as 1953, Leimdorfer first reported that the alpha blocker phentolamine had anti-arrhythmic effects. At present, some progress has been made in the study of the anti-arrhythmic mechanism of cardiac alpha receptor and alpha blockers.