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目的比较分析3种常用皮肤消毒剂(IT、CHG和PI)干预下的血培养污染率。方法以3种常用皮肤消毒剂,对需要进行血培养检查的3212例成人患者进行干预,对16 152例血培养标本进行实验室检查,分析比较各自的污染情况。结果 16 152例血培养样本中,920例为阳性,阳性率5.70%;其中,123例为污染,总体污染率为0.76%;污染菌以凝固酶阴性的葡萄球菌(CNS)为主(92/123,74.80%);PI组的污染率(0.59%)略低于IT组(0.77%)和CHG组(0.93%),但各组的污染率之间无统计学差异(P>0.05)。结论皮肤消毒剂种类的选择,不影响血培养的污染率;应从经济成本、操作简便性与挥发时间等角度考虑选用何种消毒剂;加强操作人员的技术培训、严格手消毒、严格无菌操作、加强环境管理等,才是可以显著降低血培养污染率的有效手段。
Objective To compare and analyze the blood culture contamination rates of three commonly used skin disinfectants (IT, CHG and PI). Methods Three kinds of commonly used skin disinfectants were used to intervene in 3212 adult patients who needed blood culture examination. 16 152 blood culture specimens were examined by laboratory tests, and their respective pollution status was analyzed. Results Among the 16 152 blood culture samples, 920 were positive and the positive rate was 5.70%. Among them, 123 were polluted, and the overall polluted rate was 0.76%. The coagulase-negative staphylococci (CNS) (P <0.05). The contamination rate in PI group (0.59%) was slightly lower than that in IT group (0.77%) and CHG group (0.93%). Conclusion The choice of skin disinfectants does not affect the rate of blood culture pollution; should be considered from the perspective of economic costs, ease of use and volatile time, which disinfectant to choose; strengthen technical training of operators, strict hand disinfection, strict aseptic operation , Strengthen environmental management, etc., is an effective means to significantly reduce the pollution rate of blood culture.