肌萎缩性侧索硬化(ALS)是一种慢性进行性疾病,病因不清。目前国内外罕见有效治疗报导。86年以来我们用大剂量莨菪类药物治疗16例,收到满意效果,现报告如下:临床资料一般资料:男10例,女6例;发病年龄16～60岁.平均37岁;病程平均1.5年发病因素有过劳3例;分娩后1例;感染后1例;无诱因11例。临床表现:以脊髓症状首发者12例 Amyotrophic lateral sclerosis (ALS) is a chronic, progressive disease that is etiological. At present, rare and effective treatment at home and abroad. 86 years since we treated with high-dose of drug-treatment of 16 cases, received satisfactory results are as follows: General information on clinical data: 10 males and 6 females; the age of onset of 16 to 60 years old, average 37 years; duration of an average of 1.5 The annual incidence of overworked in 3 cases; 1 after delivery; 1 case after infection; no incentive in 11 cases. Clinical manifestations: Twelve patients were diagnosed as having spinal symptoms