预混胰岛素与甘精胰岛素联合口服降糖药治疗初诊2型糖尿病的疗效比较

来源 :中国医药导报 | 被引量 : 0次 | 上传用户:fuhui
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目的:比较诺和灵30R与甘精胰岛素联合二甲双胍强化治疗初诊2型糖尿病(T2DM)的疗效。方法:80例初诊T2DM患者分为诺和灵30R组(A组,40例)和甘精胰岛素联合二甲双胍组(B组,40例),疗程3个月。比较治疗前后两组血糖控制情况及胰岛B细胞功能。结果:治疗后两组空腹血糖(FPG)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1C)均显著下降(均P〈0.01),胰岛素抵抗指数(HOMA-IR)下降(P〈0.05),胰岛素分泌指数(HOMA-β)升高(P〈0.01)。B组血糖达标更迅速。A组较B组低血
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