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冠心病的药物治疗种类繁多,抗心绞痛药中,硝酸甘油类为临床首选药物.治疗冠心病的扩血管药、β阻滞剂、血小板聚集抑制剂等有了新的发展。降脂药还没有理想的药物可以取代,近几年中草药降脂药的研究,为冠心病的治疗指出了新的途径.目前冠心病的药物治疗,主要有以下四个方面:一、抗心绞痛治疗:药物作用为增加缺血区域的灌注,减少缺血区对心脏代谢和机械作功的需要,保护心脏的功能.1、硝酸酯与亚硝酸酯类:硝酸甘油:疗效肯定,故为首选药。对于活动后发作之心脏疼痛、胸部绞窄感有缓解作用,对急性心肌梗塞之心脏疼痛无效.其主要药理作用是直接松弛血管平滑肌,使血流经侧枝循环进入缺血的心肌,降低心肌的耗氧量,因而能缓解心绞痛.过去认为硝酸甘油作用是扩张冠状循环的,现已证实对总冠状动脉血流量影
Coronary heart disease, a wide range of drug treatment, anti-anginal drugs, nitroglycerin is the drug of choice for the treatment of coronary heart disease vasodilator drugs, beta blockers, platelet aggregation inhibitors have a new development. Antihypertensive drugs are not ideal drugs can be replaced in recent years, the study of Chinese medicine lipid-lowering drugs for the treatment of coronary heart disease pointed out a new way.Currently, coronary heart disease drug treatment, mainly in the following four aspects: First, anti-angina Treatment: the role of drugs to increase the perfusion of the ischemic area, reduce the ischemic area of the heart metabolism and mechanical work needs, protect the heart’s function .1, nitrates and nitrites: nitroglycerin: efficacy is positive, so the preferred medicine. After the event for the attack of heart pain, chest strangulation relieve effect on acute myocardial infarction heart pain is invalid its main pharmacological effect is to directly relax the vascular smooth muscle, the blood flow through the collateral circulation into the ischemic myocardium, reducing myocardial Oxygen consumption, which can relieve angina in the past that the role of nitroglycerin is to expand the coronary circulation has been confirmed on total coronary blood flow shadow