论文部分内容阅读
目的:观察葶苈大枣泻肺汤加味联合顺铂治疗肺癌恶性胸腔积液的临床疗效。方法:将42例肺癌恶性胸腔积液患者随机分为治疗组和对照组,每组21例,采用胸腔内置入引流管的方法,将胸腔积液放净后,对照组用顺铂20~30mg/m2胸腔内化疗,治疗组在对照组治疗的基础上配合葶苈大枣泻肺汤加味口服,两组均每周化疗1次,4周为1个疗程,1个疗程结束后观察比较两组治疗前后胸腔积液的变化、主要症状积分、卡氏评分及不良反应发生情况。结果:治疗组在胸水疗效、临床症状积分、生活质量评分、不良反应发生情况方面均明显优于对照组(P<0.05)。结论:葶苈大枣泻肺汤加味联合顺铂可使肺癌恶性胸腔积液得到有效控制,缓解临床症状,改善生活质量,降低不良反应的发生。
Objective: To observe the curative effect of treating the malignant pleural effusion in patients with lung cancer by using Xiongzao Jujube XieFei decoction combined with cisplatin. Methods: Forty-two patients with malignant pleural effusion of lung cancer were randomly divided into treatment group and control group, with 21 cases in each group. Thirty patients with malignant pleural effusion were randomly divided into treatment group and control group. / m2 intrathoracic chemotherapy, the treatment group in the control group based on the treatment with the scallion Jujube diarrhea soup plus flavored oral administration of both groups once a week, 4 weeks for a course of treatment, a course of treatment after the end of the observation and comparison of two Before and after treatment group changes of pleural effusion, the main symptom scores, Karnofsky scores and adverse reactions. Results: The treatment group was significantly better than the control group in the efficacy of pleural effusion, clinical symptom scores, quality of life scores, and the incidence of adverse reactions (P <0.05). Conclusion: The Jiuzao Jujube Xiefei Decoction combined with cisplatin can effectively control the malignant pleural effusion of lung cancer, relieve the clinical symptoms, improve the quality of life and reduce the incidence of adverse reactions.