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胞二磷胆碱(Cytidine diphosphate choline)化学名胞嘧啶核苷二磷酸胆碱,为核苷酸衍生物,对改善脑组织代谢,促进大脑功能恢复和促进苏醒有效。大脑和中枢神经系统受到损害时都产生不同程度的代谢障碍和意识障碍,据认为,中枢神经系统损害引起的意识障碍,与脑中磷脂的减少有密切关系,而胞二磷胆碱在新陈代谢中作为辅酶参与卵磷脂的生物合成,其药理作用可能与此有关。现临床上主要用于急性颅脑外伤和脑手术所引起的意识障碍。常用量:静脉滴注一日200~600毫克,一般5~10天为一疗程。也可肌内注射,肌内注射量一日200毫克。本品无明显副作用,在临床试用中未发现毒性和不良反应,但在脑内出血急性期,不宜用大剂量。
Cytidine diphosphate choline Chemical name Cytosine diphosphate Choline, a nucleotide derivative, is effective in improving brain tissue metabolism, promoting brain function recovery and promoting wakefulness. The brain and the central nervous system are compromised have different degrees of metabolic disorders and disturbance of consciousness, it is thought that the central nervous system damage caused by disturbance of consciousness, brain phospholipid reduction are closely related to, and citicoline in the metabolism As a coenzyme involved in lecithin biosynthesis, its pharmacological effects may be related to this. Clinical is mainly used for acute craniocerebral trauma and brain surgery caused by disturbance of consciousness. Commonly used: intravenous infusion of 200 to 600 mg a day, usually 5 to 10 days for a course of treatment. Intramuscular injection can also be intramuscular injection of 200 mg on the 1st. This product has no obvious side effects, no toxicity and adverse reactions found in clinical trials, but acute bleeding in the brain, should not be used in large doses.