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目的探讨妊娠期肝内胆汁淤积症诊治中注意的几个问题。方法对2009年2月到2012年2月来我院诊治的ICP患者40例患者进行诊断,并对患者进行定期检查和药物治疗。结果治疗后40例妊娠期肝内胆汁淤积症患者瘙痒症明显得到缓解的患者有36例,占90.0%,肝功能以及CG值正常者有6例,占15.0%,肝功能有所改善并且CG值有所下降的患者有25例,占62.5%,患者的临床治疗没有明显改善有9例,占22.5%,新生胎儿早产9例,轻度窒息3例,重度窒息1例,3例胎儿死亡。37例胎儿生命体征正常,并且没有其他并发症发生。结论在临床进行诊治妊娠期肝内胆汁淤积症时,应该注意产前监护、终止妊娠时期、药物治疗以及预后等几方面的问题,对改善新生儿预后以及降低死亡率具有重要的作用。
Objective To discuss some problems in the diagnosis and treatment of intrahepatic cholestasis of pregnancy. Methods Forty patients with ICP diagnosed and treated in our hospital from February 2009 to February 2012 were diagnosed and the patients were regularly inspected and treated with drugs. Results After the treatment of 40 cases of pregnancy induced intrahepatic cholestasis patients with pruritus were significantly alleviated in 36 cases, accounting for 90.0%, liver function and normal CG values were 6 cases, accounting for 15.0%, improved liver function and CG There were 25 patients (62.5%), 9 patients (22.5%) had no clinical improvement, 9 (9) premature births, 3 mild asphyxia, 1 severe asphyxia and 3 fetal deaths . 37 cases of fetal vital signs were normal, and no other complications occurred. Conclusions In the clinical diagnosis and treatment of intrahepatic cholestasis of pregnancy, we should pay attention to several issues such as prenatal care, termination of pregnancy, drug treatment and prognosis, which play an important role in improving neonatal prognosis and reducing mortality.