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目的对比甲硝唑分别联合氧氟沙星、头孢曲松钠治疗急性化脓性阑尾炎的疗效。方法将100例急性化脓性阑尾炎患者随机分为观察组和对照组,各50例。患者术后均给予甲硝唑治疗,观察组联合头孢曲松钠治疗,对照组联合氧氟沙星治疗。对比2组患者总有效率、感染率及不良反应发生率。结果 2组临床疗效、感染率及不良反应发生率比较差异均无统计学意义(P>0.05)。结论在急性化脓性阑尾炎的术后治疗过程中,氧氟沙星与头孢曲松钠联合甲硝唑治疗方案均保持了良好的疗效,同时治疗安全性能够得到有效保障。
Objective To compare the efficacy of metronidazole with ofloxacin and ceftriaxone sodium in the treatment of acute suppurative appendicitis. Methods 100 cases of acute suppurative appendicitis were randomly divided into observation group and control group, 50 cases each. Patients were treated with metronidazole after treatment, the observation group combined with ceftriaxone sodium treatment, the control group combined with ofloxacin treatment. The total effective rate, infection rate and incidence of adverse reactions in two groups were compared. Results There was no significant difference in clinical efficacy, infection rate and incidence of adverse reactions between the two groups (P> 0.05). Conclusion In the postoperative treatment of acute suppurative appendicitis, ofloxacin and ceftriaxone sodium combined with metronidazole treatment programs have maintained a good effect, while the treatment of safety can be effectively protected.